Washington DC - President Donald Trump beleaguered labor secretary, Lori Chavez-DeRemer, announced that she will leave her post, in administration's latest major departure.

Chavez-DeRemer will take up a position in the private sector, White House communications director Steven Cheung said on X.

Her deputy, Keith Sonderling, is to lead the department's work until further notice, Cheung said.

Chavez-DeRemer has been under pressure for months over several investigations. According to reports by the Washington Post and other media, these include possible violations involving the use of budget funds and allegations of inappropriate conduct in office.

Donald Trump Trump makes moves to expand fossil fuel production for "defense readiness"

Oversight bodies are also reportedly looking into complaints about a problematic working environment at the department.

Three female employees described a hostile work environment in which staff faced retaliation, the New York Times and the New York Post reported.

Her husband was barred from the department following allegations of sexual misconduct towards employees, according to media reports.

Chavez-DeRemer rejected all allegations.

"It has been an honor and a privilege to serve in this historic Administration and work for the greatest President of my lifetime," she said in a statement.

Her appointment was seen as unusual because she held relatively union-friendly positions compared with many Republicans.

Trump had dismissed his homeland security secretary, Kristi Noem, in early March.

In early April, attorney general Pam Bondi, who had come under criticism over her handling of the Epstein case, was also forced to leave.