Patriots hand Bills first loss of season as Josh Allen makes history and other NFL news

The New England Patriots inflicted Buffalo's first defeat of the season as quarterback Drake Maye bounced back with three touchdowns in a 29-26 win, while the Los Angeles Rams surged late on the road to defeat the Philadelphia Eagles. Here's the latest NFL news.

Josh Allen (l.) of the Buffalo Bills and Drake Maye of the New England Patriots shake hands after the Patriots handed the Bills their first loss on October 4, 2026.
Josh Allen (l.) of the Buffalo Bills and Drake Maye of the New England Patriots shake hands after the Patriots handed the Bills their first loss on October 4, 2026.  © TIMOTHY T LUDWIG / GETTY IMAGES NORTH AMERICA / GETTY IMAGES VIA AFP

On a packed day of drama, the Dallas Cowboys also edged a thrilling Texas showdown in Houston, while the Indianapolis Colts ran out as winners in the NFL's latest foray to London.

New England's Maye – who reached the Super Bowl last season, but endured a nightmare start to this campaign – grabbed victory against the AFC East rival Bills, with a late go-ahead touchdown pass to Efton Chism III for a superb one-handed take.

That came after Buffalo quarterback Josh Allen appeared to have orchestrated a fourth-quarter comeback with a 34-yard hurl to Keon Coleman that made it 26-21.

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Maye ended the game with 269 passing yards and another 54 rushing yards. Romeo Doubs grabbed a pair of touchdown receptions before Chism's game-winner, which was followed by a successful two-point conversion.

Even in defeat, Allen's 88th career touchdown made him the leading touchdown scorer in Bills history.

Philadelphia looked set to pile more misery on the Rams, who entered the season as Super Bowl favorites but were 1-2 after their opening three games.

Trailing 10-20 deep in the fourth quarter, Los Angeles' underwhelming start looked likely to worsen. But a pair of late Kyren Williams touchdowns sealed a 24-20 victory, made all the more painful for the Eagles by a hamstring injury to star running back Saquon Barkley early in the game.

At Houston, CeeDee Lamb capped a superb personal performance by snaring his 17th reception of the day for a touchdown to put the Cowboys ahead 34-30 with 40 seconds remaining.

CJ Stroud attempted a 50-yard Hail Mary pass with nine seconds remaining, but could not salvage a game that the Texans had largely led.

NFL takes London by storm as Colts stomp Commanders

Ravens QB Lamar Jackson (r.) hands off the ball during the Baltimore Ravens 24-18 win over the Tennessee Titans on October 4, 2026.
Ravens QB Lamar Jackson (r.) hands off the ball during the Baltimore Ravens 24-18 win over the Tennessee Titans on October 4, 2026.  © PATRICK SMITH / GETTY IMAGES NORTH AMERICA / GETTY IMAGES VIA AFP

In the NFL's latest London game, Indianapolis running back Jonathan Taylor ran for two touchdowns as the Colts defeated the injury-hit Washington Commanders 30-13.

Taylor had ample opportunity to unveil his London-themed celebration, miming sipping tea after finding the end zone late in the first half at Tottenham Hotspur Stadium and again early in the third quarter to give the Colts a 17-6 lead.

"The crowd was electric, the energy was amazing, and I can't wait to come back to London," said Taylor at the Tottenham Hotspur Stadium.

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Elsewhere, Baltimore defeated the hapless Tennessee Titans 24-18, though the victory was tarnished by an ankle injury for quarterback Lamar Jackson, who did not return after halftime.

The New York Giants sealed a 36-24 win over Arizona with a walk-off pick-six. With Cardinals quarterback Jacoby Brissett seeking a late go-ahead touchdown, cornerback Deonte Banks intercepted and raced 98 yards to the opposite end zone.

The Jacksonville Jaguars improved to 3-1 with a victory over Cincinnati, the Chicago Bears eased past the New York Jets 23-12 thanks to two Kyle Monangai rushing touchdowns, and Green Bay edged Tampa Bay 17-14.

Cover photo: TIMOTHY T LUDWIG / GETTY IMAGES NORTH AMERICA / GETTY IMAGES VIA AFP

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