Syracuse, Italy - A Gaza-bound boat carrying pro-Palestinian activists and humanitarian aid left Sicily on Sunday, over a month after Israel detained and deported people aboard a previous vessel.

The Handala, operated by the Freedom Flotilla Coalition, left the port of Syracuse shortly after 12:00 PM (6:00 AM ET), an AFP journalist saw, carrying about fifteen activists.

Several dozen people, some holding Palestinian flags and others wearing keffiyeh scarves, gathered at the port to cheer the boat's departure with cries of "Free Palestine".

The former Norwegian trawler – loaded with medical supplies, food, children's equipment and medicine – will sail for about a week in the Mediterranean, covering roughly 1,120 miles, in the hope of reaching Gaza's coast.

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In early March, Israel imposed a total aid blockade on Gaza amid an impasse in truce negotiations, only partially easing restrictions in late May.

The boat will make a stop at Gallipoli, in southeastern Italy, where two members of the hard-left France Unbowed party (LFI) are expected to join.

The initiative comes six weeks after the departure of the Madleen, another ship that left Italy for Gaza transporting aid and activists, including Greta Thunberg.

Israel authorities intercepted the Madleen about 115 miles west of Gaza's coast.

"This is a mission for the children in Gaza, to break the humanitarian blockade and to break the summer silence on the genocide," said Gabrielle Cathala, one of the two France Unbowed party members set to board the boat on July 18.

"I hope we will reach Gaza but if not, it will be yet another violation of international law" by Israel, she added.